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Efficient, precise, and expansive, RAvIN redefines nucleoside synthesis to power next-generation RNA therapeutics

RAvINs groundbreaking chemistry streamlines synthesis and maximizes the chemical diversity required to create clinically viable RNA medicines.

Streamlined synthesis of med chem ready nucleoside cores means:

Enhanced Drug Performance​
  • Expanded chemical space
  • Improved ADMET profile
  • Extrahepatic distribution
  • BBB crossing
Enhanced Manufacturing
  • Lowered production costs
  • Greener route to RNA therapeutics
  • Single-component, homogeneous chemical entities displaying precise stoichiometry
  • Faster manufacture = personalized medicine enabling 
Example of application: Six high-value nucleoside analogs, produced with the RAvIN platform vs. conventional methods
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NB = Thymine

Business Title

With its expanding library of nucleoside analogs, RAvIN allows for rapid, rational, and unprecedented fine-tuning of RNA medicines to address ADMET issues, a significant advantage over conventional modifications that often lead to attrition.

Conventional
modifications
Cloudburst-enabled
modifications
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VS
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CLOUDBURST

BIOTECH

Cloudburst is a seed-stage platform company actively developing an expanding library of structurally tailored nucleoside analogs to create medicines that target undruggable or rare diseases. 

8999 Nelson Way
Burnaby, BC

V5A 4B5

Canada

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